Effect of protracted dexamethasone exposure and its withdrawal on rocuronium-induced neuromuscular blockade and sugammadex reversal: an ex vivo rat study

Studies have reported that protracted dexamethasone treatment induces resistance to nondepolarizing neuromuscular blocking agents (NMBAs) and the association with nicotinic acetylcholine receptors in the diaphragm of rats. Here, we investigated the effect of protracted dexamethasone administration o...

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Udgivet i:Sci Rep
Main Authors: Oh, Seok Kyeong, Lim, Byung Gun, Park, Sungsoo, Yang, Hong Seuk, In, Junyong, Kim, Yong Beom, Choi, Hey-ran, Lee, Il Ok
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677897/
https://ncbi.nlm.nih.gov/pubmed/31375743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47784-3
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