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LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc

Long non-coding RNAs (lncRNAs) contribute to colorectal cancer (CRC). However, the role of lncRNAs in CRC metabolism, especially glucose metabolism remains largely unknown. In this study, we identify a lncRNA, GLCC1, which is significantly upregulated under glucose starvation in CRC cells, supportin...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Tang, Jiayin, Yan, Tingting, Bao, Yujie, Shen, Chaoqin, Yu, Chenyang, Zhu, Xiaoqiang, Tian, Xianglong, Guo, Fangfang, Liang, Qian, Liu, Qiang, Zhong, Ming, Chen, Jinxian, Ge, Zhizheng, Li, Xiaobo, Chen, Xiaoyu, Cui, Yun, Chen, Yingxuan, Zou, Weiping, Chen, Haoyan, Hong, Jie, Fang, Jing-Yuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677832/
https://ncbi.nlm.nih.gov/pubmed/31375671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11447-8
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