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Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes

Immune tolerance to allografts has been pursued for decades as an important goal in transplantation. Administration of apoptotic donor splenocytes effectively induces antigen-specific tolerance to allografts in murine studies. Here we show that two peritransplant infusions of apoptotic donor leukocy...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Singh, Amar, Ramachandran, Sabarinathan, Graham, Melanie L., Daneshmandi, Saeed, Heller, David, Suarez-Pinzon, Wilma Lucia, Balamurugan, Appakalai N., Ansite, Jeffrey D., Wilhelm, Joshua J., Yang, Amy, Zhang, Ying, Palani, Nagendra P., Abrahante, Juan E., Burlak, Christopher, Miller, Stephen D., Luo, Xunrong, Hering, Bernhard J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677762/
https://ncbi.nlm.nih.gov/pubmed/31375697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11338-y
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