Evolution of the rodent Trim5 cluster is marked by divergent paralogous expansions and independent acquisitions of TrimCyp fusions

Evolution of cellular innate immune genes in response to viral threats represents a rich area of study for understanding complex events that shape mammalian genomes. One of these genes, TRIM5, is a retroviral restriction factor that mediates a post-entry block to infection. Previous studies on the g...

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Vydáno v:Sci Rep
Hlavní autoři: Boso, Guney, Shaffer, Esther, Liu, Qingping, Cavanna, Kathryn, Buckler-White, Alicia, Kozak, Christine A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677749/
https://ncbi.nlm.nih.gov/pubmed/31375773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47720-5
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