Metabolites of type I, II, III, and IV collagen may serve as markers of disease activity in axial spondyloarthritis

Local inflammation in axial spondyloarthritis (axSpA) leads to the release of collagen metabolites from the disease-affected tissue. We investigated whether collagen metabolites were associated with disease activity and could distinguish non-radiographic(nr)-axSpA from ankylosing spondylitis (AS). A...

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Pubblicato in:Sci Rep
Autori principali: Hušáková, Markéta, Bay-Jensen, Anne-C., Forejtová, Šárka, Zegzulková, Kateřina, Tomčík, Michal, Gregová, Monika, Bubová, Kristýna, Hořínková, Jana, Gatterová, Jindra, Pavelka, Karel, Siebuhr, Anne Sofie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677742/
https://ncbi.nlm.nih.gov/pubmed/31375691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47502-z
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