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Intervention changes acoustic peak frequency and mesolimbic neurochemistry in the Pink1-/- rat model of Parkinson disease

The neural mechanisms underlying behavioral therapy for vocal acoustic deficits in patients with Parkinson disease is unknown. A primary hypothesis is that voice therapy may modulate mesolimbic brainstem regions, including the ventral tegmental area (VTA). The VTA is implicated in ultrasonic call pe...

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Veröffentlicht in:PLoS One
Hauptverfasser: Stevenson, Sharon A., Ciucci, Michelle R., Kelm-Nelson, Cynthia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677310/
https://ncbi.nlm.nih.gov/pubmed/31374106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220734
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