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Local mu-opioid receptor antagonism blunts evoked phasic dopamine release in the nucleus accumbens of rats

Mu-opioid receptors (MORs) in the nucleus accumbens (NAc) can regulate reward-related behaviors that are dependent on mesolimbic dopamine, but the precise mechanism of this MOR regulation is unknown. We hypothesized that MORs within the NAc core regulate dopamine release. Specifically, we infused th...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Gómez-A, Alexander, Shnitko, Tatiana A., Barefoot, Haley M., Brightbill, Eleanor L., Sombers, Leslie A., Nicola, Saleem M., Robinson, Donita L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677254/
https://ncbi.nlm.nih.gov/pubmed/30388365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00437
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