Mapping cis-Regulatory Chromatin Contacts in Neural Cells Links Neuropsychiatric Disorder Risk Variants to Target Genes

Mutations in gene regulatory elements have been associated with a wide range of complex neuropsychiatric disorders. However, due to their cell-type specificity and difficulties in characterizing their regulatory targets, the ability to identify causal genetic variants has remained limited. To addres...

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Publicado no:Nat Genet
Main Authors: Song, Michael, Yang, Xiaoyu, Ren, Xingjie, Maliskova, Lenka, Li, Bingkun, Jones, Ian, Wang, Chao, Jacob, Fadi, Wu, Kenneth, Traglia, Michela, Tam, Tsz Wai, Jamieson, Kirsty, Lu, Si-Yao, Ming, Guo-Li, Li, Yun, Yao, Jun, Weiss, Lauren A., Dixon, Jesse, Judge, Luke M., Conklin, Bruce R., Song, Hongjun, Gan, Li, Shen, Yin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677164/
https://ncbi.nlm.nih.gov/pubmed/31367015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0472-1
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