TNF-α-Producing Cryptococcus neoformans Exerts Protective Effects on Host Defenses in Murine Pulmonary Cryptococcosis

Tumor necrosis factor alpha (TNF-α) plays a critical role in the control of cryptococcal infection, and its insufficiency promotes cryptococcal persistence. To explore the therapeutic potential of TNF-α supplementation as a booster of host anti-cryptococcal responses, we engineered a C. neoformans s...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Fa, Zhenzong, Xu, Jintao, Yi, Jiu, Sang, Junjun, Pan, Weihua, Xie, Qun, Yang, Runping, Fang, Wei, Liao, Wanqing, Olszewski, Michal A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677034/
https://ncbi.nlm.nih.gov/pubmed/31404168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01725
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