Helical and kinase domain mutations of PIK3CA, and their association with hormone receptor expression in breast cancer

Breast cancer is one of the major causes of female morbidity and mortality, accounting for ~25% of the total cancer cases in women. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic α subunit (PIK3CA) mutations serve a major role in downstream signaling of receptor tyrosine kinases. The prese...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Vatte, Chittibabu, Al Amri, Ali Mohammed, Cyrus, Cyril, Chathoth, Shahanas, Alsayyah, Ahmed, Ahmad, Arafat, Akhtar, Mohammed Shakil, Alrashidi, Nada Fehaid, Jayaseeli, Nithya, Al Wadani, Hamed, Al Zahrani, Alhussain, Al Ali, Amein Kadhem
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2019
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676675/
https://ncbi.nlm.nih.gov/pubmed/31404155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10565
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