Helical and kinase domain mutations of PIK3CA, and their association with hormone receptor expression in breast cancer

Breast cancer is one of the major causes of female morbidity and mortality, accounting for ~25% of the total cancer cases in women. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic α subunit (PIK3CA) mutations serve a major role in downstream signaling of receptor tyrosine kinases. The prese...

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Gepubliceerd in:Oncol Lett
Hoofdauteurs: Vatte, Chittibabu, Al Amri, Ali Mohammed, Cyrus, Cyril, Chathoth, Shahanas, Alsayyah, Ahmed, Ahmad, Arafat, Akhtar, Mohammed Shakil, Alrashidi, Nada Fehaid, Jayaseeli, Nithya, Al Wadani, Hamed, Al Zahrani, Alhussain, Al Ali, Amein Kadhem
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676675/
https://ncbi.nlm.nih.gov/pubmed/31404155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10565
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