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Helical and kinase domain mutations of PIK3CA, and their association with hormone receptor expression in breast cancer
Breast cancer is one of the major causes of female morbidity and mortality, accounting for ~25% of the total cancer cases in women. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic α subunit (PIK3CA) mutations serve a major role in downstream signaling of receptor tyrosine kinases. The prese...
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| Publicado no: | Oncol Lett |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6676675/ https://ncbi.nlm.nih.gov/pubmed/31404155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10565 |
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