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Helical and kinase domain mutations of PIK3CA, and their association with hormone receptor expression in breast cancer
Breast cancer is one of the major causes of female morbidity and mortality, accounting for ~25% of the total cancer cases in women. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic α subunit (PIK3CA) mutations serve a major role in downstream signaling of receptor tyrosine kinases. The prese...
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| Published in: | Oncol Lett |
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| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
D.A. Spandidos
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6676675/ https://ncbi.nlm.nih.gov/pubmed/31404155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10565 |
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