Combination of metformin and p38 MAPK inhibitor, SB203580, reduced myocardial ischemia/reperfusion injury in non-obese type 2 diabetic Goto-Kakizaki rats

Diabetic cardiomyopathy, especially myocardial ischemia reperfusion (I/R) injury, is a major cause of morbidity and mortality in type 2 diabetic patients. The increasing of basal p38 MAP Kinase (p38 MAPK) activation is a major factor that aggravates cardiac death on diabetic cardiomyopathy. In addit...

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Publicado no:Exp Ther Med
Main Authors: Sanit, Jantira, Prompunt, Eakkapote, Adulyaritthikul, Punyanuch, Nokkaew, Nuttikarn, Mongkolpathumrat, Podsawee, Kongpol, Kantapich, Kijtawornrat, Anusak, Petchdee, Soontaree, Barrère-Lemaire, Stephanie, Kumphune, Sarawut
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676201/
https://ncbi.nlm.nih.gov/pubmed/31410128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7763
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