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Methylation-regulated ZNF545 inhibits growth of the p53-mutant KYSE150 cell line by inducing p21 and Bax

The Krüppel-associated box zinc-finger protein 545 (ZNF545) was recently identified as a tumor suppressor in esophageal squamous cell carcinoma (ESCC). However, the role of ZNF545 in the tumorigenesis of esophageal cancer cells expressing loss-of-function mutant p53 has not been elucidated. In the p...

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Pubblicato in:Exp Ther Med
Autori principali: Fan, Yu, Wang, Yu, Fu, Shaozhi, Liu, Duan, Lin, Sheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676145/
https://ncbi.nlm.nih.gov/pubmed/31410110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7737
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