Species-Specific Colocalization of Middle East Respiratory Syndrome Coronavirus Attachment and Entry Receptors

Middle East respiratory syndrome coronavirus (MERS-CoV) uses the S1(B) domain of its spike protein to bind to dipeptidyl peptidase 4 (DPP4), its functional receptor, and its S1(A) domain to bind to sialic acids. The tissue localization of DPP4 in humans, bats, camelids, pigs, and rabbits generally c...

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Publicado en:J Virol
Autores principales: Widagdo, W., Okba, Nisreen M. A., Li, Wentao, de Jong, Alwin, de Swart, Rik L., Begeman, Lineke, van den Brand, Judith M. A., Bosch, Berend-Jan, Haagmans, Bart L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2019
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675889/
https://ncbi.nlm.nih.gov/pubmed/31167913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00107-19
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