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CD28 Costimulation Is Required for Development of Herpetic Stromal Keratitis but Does Not Prevent Establishment of Latency

Corneal infection with herpes simplex virus 1 (HSV-1) leads to infection of trigeminal ganglia (TG), typically followed by the establishment of latency in the infected neurons. When latency is disrupted, the virus reactivates and migrates back to the cornea, where it restimulates the immune response...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Yin, Xiao-Tang, Baugnon, Nicholas K., Potter, Chloe A., Tai, Shannon, Keadle, Tammie L., Stuart, Patrick M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675882/
https://ncbi.nlm.nih.gov/pubmed/31167920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00659-19
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