Pectasol‐C Modified Citrus Pectin targets Galectin‐3‐induced STAT3 activation and synergize paclitaxel cytotoxic effect on ovarian cancer spheroids

Here we sought to determine the relationship between STAT3 activity and Galectin‐3 (Gal‐3) and to investigate the cytotoxic effect of PectaSol‐C Modified Citrus Pectin (Pect‐MCP) as a specific competitive inhibitor of Galectin‐3 (Gal‐3) in combination with Paclitaxel (PTX) to kill the ovarian cancer...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Hossein, Ghamartaj, Halvaei, Sina, Heidarian, Yassaman, Dehghani‐Ghobadi, Zeinab, Hassani, Mina, Hosseini, Homa, Naderi, Nima, Sheikh Hassani, Shahrzad
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675724/
https://ncbi.nlm.nih.gov/pubmed/31197964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2334
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