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Engineering macrophages to phagocytose cancer cells by blocking the CD47/SIRPɑ axis
The use of immunotherapy has achieved great advances in the treatment of cancer. Macrophages play a pivotal role in the immune defense system, serving both as phagocytes (removal of pathogens and cancer cells) and as antigen‐presenting cells (activation of T cells). However, research regarding tumor...
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| Publicado no: | Cancer Med |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6675709/ https://ncbi.nlm.nih.gov/pubmed/31183992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2332 |
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