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Two-Pore Channel 2 activity is required for slow muscle cell-generated Ca(2+) signaling during myogenesis in intact zebrafish

We have recently characterized essential inositol 1,4,5-trisphosphate receptor (IP(3)R) and ryanodine receptor (RyR)-mediated Ca(2+) signals generated during the differentiation of slow muscle cells (SMCs) in intact zebrafish embryos. Here, we show that the lysosomal two-pore channel 2 (TPC2) also p...

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Detalhes bibliográficos
Publicado no:Int J Dev Biol
Main Authors: Kelu, Jeffrey J., Chan, Hayley L.H., Webb, Sarah E., Cheng, Arthur H.H., Ruas, Margarida, Parrington, John, Galione, Antony, Miller, Andrew L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675607/
https://ncbi.nlm.nih.gov/pubmed/26679948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1387/ijdb.150206am
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