Morphine and Pain-Related Stimuli Enhance Cell Surface Availability of Somatic δ-Opioid Receptors in Rat Dorsal Root Ganglia

The present study demonstrates that perikaryalδ-opioid receptors (δORs) in rat dorsal root ganglion (DRG) neurons bind and internalize opioid ligands circulating in the CSF. Using confocal and electron microscopy, we found that prolonged morphine treatment increased the cell surface density of these...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Gendron, Louis, Lucido, Anna Lisa, Mennicken, Françoise, O'Donnell, Dajan, Vincent, Jean-Pierre, Stroh, Thomas, Beaudet, Alain
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2006
Sujets:
Cellular/Molecular
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675352/
https://ncbi.nlm.nih.gov/pubmed/16421315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3598-05.2006
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