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Environmental Enrichment Enhances Neurogranin Expression and Hippocampal Learning and Memory But Fails to Rescue the Impairments of Neurogranin Null Mutant Mice

Environmental enrichment is known to enhance hippocampal neurogenesis and cognitive functions. Neurogranin (Ng), a specific substrate of protein kinase C (PKC), is abundantly expressed in brain regions important for cognitive functions. Deletion of Ng in mice causes severe deficits in spatial learni...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Huang, Freesia L., Huang, Kuo-Ping, Wu, Junfang, Boucheron, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675199/
https://ncbi.nlm.nih.gov/pubmed/16763030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1182-06.2006
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