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d-Aspartate Regulates Melanocortin Formation and Function: Behavioral Alterations in d-Aspartate Oxidase-Deficient Mice
D-Aspartate, an abundant d-amino acid enriched in neuroendocrine tissues, can be degraded by d-aspartate oxidase (Ddo). To elucidate the function of d-aspartate, we generated mice with targeted deletion of Ddo (Ddo(−/−)) and observe massive but selective augmentations of d-aspartate in various tissu...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6675153/ https://ncbi.nlm.nih.gov/pubmed/16525061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5060-05.2006 |
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