Targeted sequencing of candidate genes of dyslipidemia in Punjabi Sikhs: Population-specific rare variants in GCKR promote ectopic fat deposition

Dyslipidemia is a well-established risk factor for cardiovascular diseases. Although, advances in genome-wide technologies have enabled the discovery of hundreds of genes associated with blood lipid phenotypes, most of the heritability remains unexplained. Here we performed targeted resequencing of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sanghera, Dharambir K., Hopkins, Ruth, Malone-Perez, Megan W., Bejar, Cynthia, Tan, Chengcheng, Mussa, Huda, Whitby, Paul, Fowler, Ben, Rao, Chinthapally V., Fung, KarMing A., Lightfoot, Stan, Frazer, J. Kimble
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675050/
https://ncbi.nlm.nih.gov/pubmed/31369557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211661
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