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Suppression of Microglial Inflammatory Activity by Myelin Phagocytosis: Role of p47-PHOX-Mediated Generation of Reactive Oxygen Species

Multiple sclerosis (MS) is pathologically characterized by inflammatory demyelination and neuronal injury. Although phagocytosis of myelin debris by microglia and macrophages in acute MS lesions is well documented, its pathophysiological significance is unclear. Using real-time quantitative PCR, flo...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Liu, Yang, Hao, Wenlin, Letiembre, Maryse, Walter, Silke, Kulanga, Miroslav, Neumann, Harald, Fassbender, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674962/
https://ncbi.nlm.nih.gov/pubmed/17167081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2531-06.2006
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