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Tumor Necrosis Factor-α Mediates Oligodendrocyte Death and Delayed Retinal Ganglion Cell Loss in a Mouse Model of Glaucoma

Glaucoma is a widespread ocular disease characterized by a progressive loss of retinal ganglion cells (RGCs). Previous studies suggest that the cytokine tumor necrosis factor-α (TNF-α) may contribute to the disease process, although its role in vivo and its mechanism of action are unclear. To invest...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Nakazawa, Toru, Nakazawa, Chifuyu, Matsubara, Akihisa, Noda, Kousuke, Hisatomi, Toshio, She, Haicheng, Michaud, Norman, Hafezi-Moghadam, Ali, Miller, Joan W., Benowitz, Larry I.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674838/
https://ncbi.nlm.nih.gov/pubmed/17151265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2801-06.2006
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