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Estrogen Receptor Protein Interaction with Phosphatidylinositol 3-Kinase Leads to Activation of Phosphorylated Akt and Extracellular Signal-Regulated Kinase 1/2 in the Same Population of Cortical Neurons: A Unified Mechanism of Estrogen Action
17β-Estradiol (E(2))-induced neuroprotection is dependent on mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase (PI3K) signaling cascades. We sought to determine whether E(2) neuroprotective mechanisms are mediated by a unified signaling cascade activated by estrogen receptor...
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| Publicado no: | J Neurosci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6674594/ https://ncbi.nlm.nih.gov/pubmed/16971528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1443-06.2006 |
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