Enhancing GABA(A) Receptor α1 Subunit Levels in Hippocampal Dentate Gyrus Inhibits Epilepsy Development in an Animal Model of Temporal Lobe Epilepsy

Differential expression of GABA(A) receptor (GABR) subunits has been demonstrated in hippocampus from patients and animals with temporal lobe epilepsy (TLE), but whether these changes are important for epileptogenesis remains unknown. Previous studies in the adult rat pilocarpine model of TLE found...

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Pubblicato in:J Neurosci
Autori principali: Raol, YogendraSinh H, Lund, Ingrid V, Bandyopadhyay, Sabita, Zhang, Guojun, Roberts, Daniel S, Wolfe, John H, Russek, Shelley J, Brooks-Kayal, Amy R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2006
Soggetti:
Brief Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674546/
https://ncbi.nlm.nih.gov/pubmed/17079662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3329-06.2006
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