Increased Citrullination of Histone H3 in Multiple Sclerosis Brain and Animal Models of Demyelination: A Role for Tumor Necrosis Factor-Induced Peptidylarginine Deiminase 4 Translocation

Modification of arginine residues by citrullination is catalyzed by peptidylarginine deiminases (PADs), of which five are known, generating irreversible protein structural modifications. We have shown previously that enhanced citrullination of myelin basic protein contributed to destabilization of t...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Mastronardi, Fabrizio G., Wood, D. Denise, Mei, Jiang, Raijmakers, Reinout, Tseveleki, Vivian, Dosch, Hans-Michael, Probert, Lesley, Casaccia-Bonnefil, Patrizia, Moscarello, Mario A.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674531/
https://ncbi.nlm.nih.gov/pubmed/17079667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3349-06.2006
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