Neurotrophin-3 Gradients Established by Lentiviral Gene Delivery Promote Short-Distance Axonal Bridging beyond Cellular Grafts in the Injured Spinal Cord

Neurotrophic factor delivery to sites of spinal cord injury (SCI) promotes axon growth into but not beyond lesion sites. We tested the hypothesis that sustained growth factor gradients beyond regions of SCI will promote significant axonal bridging into and beyond lesions. Adult rats underwent C3 les...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Taylor, Laura, Jones, Leonard, Tuszynski, Mark H., Blesch, Armin
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2006
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674461/
https://ncbi.nlm.nih.gov/pubmed/16988042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0734-06.2006
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