Late Developmental Stage-Specific Role of Tryptophan Hydroxylase 1 in Brain Serotonin Levels

Serotonin [5-hydroxytryptamine (5-HT)] is a major therapeutic target of psychiatric disorders. Tryptophan hydroxylase (TPH) catalyzes the rate-limiting reaction in the biosynthesis of 5-HT. Two isoforms (TPH1 and TPH2) having tryptophan hydroxylating activity were identified. Association studies hav...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Nakamura, Kazuhiro, Sugawara, Yuko, Sawabe, Keiko, Ohashi, Akiko, Tsurui, Hiromichi, Xiu, Yan, Ohtsuji, Mareki, Lin, Qing Shun, Nishimura, Hiroyuki, Hasegawa, Hiroyuki, Hirose, Sachiko
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674418/
https://ncbi.nlm.nih.gov/pubmed/16407550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1835-05.2006
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