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Central Roles of the Roof Plate in Telencephalic Development and Holoprosencephaly
The roof plate is a well known signaling center in CNS development, but its roles in the developing telencephalon and the common holoprosencephaly (HPE) malformation have been uncertain. Using cellular ablations in mice, we show that roof plate cell loss causes failed midline induction and HPE in th...
Gespeichert in:
| Veröffentlicht in: | J Neurosci |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6674267/ https://ncbi.nlm.nih.gov/pubmed/16855091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0714-06.2006 |
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