Antibodies against the NG2 Proteoglycan Promote the Regeneration of Sensory Axons within the Dorsal Columns of the Spinal Cord

The NG2 chondroitin sulfate proteoglycan inhibits axon growth in vitro. Levels of NG2 increase rapidly in the glial scars that form at sites of CNS injury, suggesting that NG2 may inhibit axon regeneration. To determine the functions of NG2, we infused mixtures of neutralizing or non-neutralizing an...

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Pubblicato in:J Neurosci
Autori principali: Tan, Andrew M., Colletti, Mario, Rorai, Ann T., Skene, J. H. Pate, Levine, Joel M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674154/
https://ncbi.nlm.nih.gov/pubmed/16672645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3900-05.2006
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