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Distinct Physiological Mechanisms Underlie Altered Glycinergic Synaptic Transmission in the Murine Mutants spastic, spasmodic, and oscillator

Spastic (spa), spasmodic (spd), and oscillator (ot) mice have naturally occurring glycine receptor (GlyR) mutations, which manifest as motor deficits and an exaggerated “startle response.” Using whole-cell recording in hypoglossal motoneurons, we compared the physiological mechanisms by which each m...

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Pubblicato in:J Neurosci
Autori principali: Graham, Brett A., Schofield, Peter R., Sah, Pankaj, Margrie, Troy W., Callister, Robert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674148/
https://ncbi.nlm.nih.gov/pubmed/16672662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3991-05.2006
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