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Activation of Group III Metabotropic Glutamate Receptors Attenuates Rotenone Toxicity on Dopaminergic Neurons through a Microtubule-Dependent Mechanism

Systemic administration of rotenone, a widely used pesticide, causes selective degeneration of nigral dopaminergic (DA) neurons and Parkinson’s disease-like symptoms in animal models. Our previous study has shown that the microtubule-depolymerizing activity of rotenone plays a critical role in its s...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Jiang, Qian, Yan, Zhen, Feng, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674015/
https://ncbi.nlm.nih.gov/pubmed/16624952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0118-06.2006
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