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Sustained Elevation of Dendritic Calcium Evokes Widespread Endocannabinoid Release and Suppression of Synapses onto Cerebellar Purkinje Cells

Endocannabinoids can act as retrograde messengers that allow postsynaptic cells to regulate the strength of their synaptic inputs. In the cerebellum, Purkinje cells (PCs) release endocannabinoids through two mechanisms. Synaptic activation evokes local endocannabinoid release that relies on a pathwa...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Brenowitz, Stephan D., Best, Aaron R., Regehr, Wade G.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673843/
https://ncbi.nlm.nih.gov/pubmed/16793891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1280-06.2006
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