Spatial Gradient of Microstructural Changes in Normal-Appearing White Matter in Tracts Affected by White Matter Hyperintensities in Older Age

Background and Purpose: White matter hyperintensities (WMH) are commonly seen on structural MRI of older adults and are a manifestation of underlying and adjacent tissue damage. WMH may contribute to cortical disconnection and cognitive dysfunction, but it is unclear how WMH affect intersecting or n...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Muñoz Maniega, Susana, Meijboom, Rozanna, Chappell, Francesca M., Valdés Hernández, Maria del C., Starr, John M., Bastin, Mark E., Deary, Ian J., Wardlaw, Joanna M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673707/
https://ncbi.nlm.nih.gov/pubmed/31404147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2019.00784
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