Glycogen synthase kinase-3β inhibition enhances myelination in preterm newborns with intraventricular hemorrhage, but not recombinant Wnt3A

Intraventricular hemorrhage (IVH) in preterm infants results in reduced proliferation and maturation of oligodendrocyte progenitor cells (OPCs), and survivors exhibit reduced myelination and neurological deficits. Wnt signaling regulates OPC maturation and myelination in a context dependent manner....

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Dohare, Preeti, Cheng, Bokun, Ahmed, Ehsan, Yadala, Vivek, Singla, Pranav, Thomas, Sunisha, Kayton, Robert, Ungvari, Zoltan, Ballabh, Praveen
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673662/
https://ncbi.nlm.nih.gov/pubmed/29940337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2018.06.015
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