A Mutation in the Cone-Specific pde6 Gene Causes Rapid Cone Photoreceptor Degeneration in Zebrafish

Photoreceptor degeneration is a common cause of inherited blindness worldwide. We have identified a blind zebrafish mutant with rapid degeneration of cone photoreceptors caused by a mutation in the cone phosphodiesterase c (pde6c) gene, a key regulatory component in cone phototransduction. Some rods...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Stearns, George, Evangelista, Meradelfa, Fadool, James M., Brockerhoff, Susan E.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673616/
https://ncbi.nlm.nih.gov/pubmed/18077698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3136-07.2007
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