Inhibiting Glycosaminoglycan Chain Polymerization Decreases the Inhibitory Activity of Astrocyte-Derived Chondroitin Sulfate Proteoglycans

Chondroitin sulfate proteoglycans (CSPGs) are upregulated in the CNS after injury and participate in the inhibition of axon regeneration mainly through their glycosaminoglycan (GAG) side chains. In the present study, we have identified a new way to alleviate the inhibition of axonal regeneration by...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Laabs, Tracy L., Wang, Hang, Katagiri, Yasuhiro, McCann, Thomas, Fawcett, James W., Geller, Herbert M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2007
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673453/
https://ncbi.nlm.nih.gov/pubmed/18160657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2807-07.2007
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