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Exogenous Delivery of Heat Shock Protein 70 Increases Lifespan in a Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disorder that results in the progressive loss of motoneurons (MNs) in the CNS. Several survival and death mechanisms of MNs have been characterized and it has been determined that MNs do not appear to mount a complete stress res...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Gifondorwa, David J., Robinson, Mac B., Hayes, Crystal D., Taylor, Anna R., Prevette, David M., Oppenheim, Ronald W., Caress, James, Milligan, Carolanne E.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673412/
https://ncbi.nlm.nih.gov/pubmed/18045911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4057-07.2007
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