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Exogenous Delivery of Heat Shock Protein 70 Increases Lifespan in a Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disorder that results in the progressive loss of motoneurons (MNs) in the CNS. Several survival and death mechanisms of MNs have been characterized and it has been determined that MNs do not appear to mount a complete stress res...

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Detalhes bibliográficos
Publicado no:J Neurosci
Principais autores: Gifondorwa, David J., Robinson, Mac B., Hayes, Crystal D., Taylor, Anna R., Prevette, David M., Oppenheim, Ronald W., Caress, James, Milligan, Carolanne E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673412/
https://ncbi.nlm.nih.gov/pubmed/18045911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4057-07.2007
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