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High-Frequency Deep Brain Stimulation of the Nucleus Accumbens Region Suppresses Neuronal Activity and Selectively Modulates Afferent Drive in Rat Orbitofrontal Cortex In Vivo

High-frequency deep-brain stimulation (DBS) of the nucleus accumbens (NAc) region is an effective therapeutic avenue for patients with treatment-resistant obsessive–compulsive disorder (OCD). Imaging studies suggest that DBS acts by suppressing the aberrant metabolism in the orbitofrontal cortex (OF...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: McCracken, Clinton B., Grace, Anthony A.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673308/
https://ncbi.nlm.nih.gov/pubmed/18003839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3750-07.2007
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