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Characterization of the Kynurenine Pathway in Human Neurons

The kynurenine pathway is a major route of l-tryptophan catabolism producing neuroactive metabolites implicated in neurodegeneration and immune tolerance. We characterized the kynurenine pathway in human neurons and the human SK-N-SH neuroblastoma cell line and found that the kynurenine pathway enzy...

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Pubblicato in:J Neurosci
Autori principali: Guillemin, Gilles J., Cullen, Karen M., Lim, Chai K., Smythe, George A., Garner, Brett, Kapoor, Vimal, Takikawa, Osamu, Brew, Bruce J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673280/
https://ncbi.nlm.nih.gov/pubmed/18032661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4101-07.2007
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