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Postsynaptic Secretion of BDNF and NT-3 from Hippocampal Neurons Depends on Calcium–Calmodulin Kinase II Signaling and Proceeds via Delayed Fusion Pore Opening

The mammalian neurotrophins (NTs) NGF, BDNF, NT-3, and NT-4 constitute a family of secreted neuronal growth factors. In addition, NTs are implicated in several forms of activity-dependent synaptic plasticity. Although synaptic secretion of NTs has been described, the intracellular signaling cascades...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Kolarow, Richard, Brigadski, Tanja, Lessmann, Volkmar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2007
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673152/
https://ncbi.nlm.nih.gov/pubmed/17898207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0692-07.2007
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