Endogenous Transforming Growth Factor β1 Suppresses Inflammation and Promotes Survival in Adult CNS

Transforming growth factor β1 (TGFβ1) is a pleiotropic cytokine with potent neurotrophic and immunosuppressive properties that is upregulated after injury, but also expressed in the normal nervous system. In the current study, we examined the regulation of TGFβ1 and the effects of TGFβ1 deletion on...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Makwana, Milan, Jones, Leonard L., Cuthill, Dan, Heuer, Heike, Bohatschek, Marion, Hristova, Mariya, Friedrichsen, Sönke, Ormsby, Ilona, Bueringer, Dietmute, Koppius, Andrea, Bauer, Karl, Doetschman, Thomas, Raivich, Gennadij
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2007
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673043/
https://ncbi.nlm.nih.gov/pubmed/17942715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2255-07.2007
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