Neuregulin1 (NRG1) Signaling through Fyn Modulates NMDA Receptor Phosphorylation: Differential Synaptic Function in NRG1(+/−) Knock-Outs Compared with Wild-Type Mice

We previously identified Neuregulin1 (NRG1) as a gene contributing to the risk of developing schizophrenia. Furthermore, we showed that NRG1(+/−) mutant mice display behavioral abnormalities that are reversed by clozapine, an atypical antipsychotic drug used for the treatment of schizophrenia. We no...

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Publicat a:J Neurosci
Autors principals: Bjarnadottir, Maria, Misner, Dinah L., Haverfield-Gross, Sascha, Bruun, Silas, Helgason, Vignir G., Stefansson, Hreinn, Sigmundsson, Arnar, Firth, David R., Nielsen, Berit, Stefansdottir, Ragnheidur, Novak, Thomas J., Stefansson, Kari, Gurney, Mark E., Andresson, Thorkell
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2007
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672983/
https://ncbi.nlm.nih.gov/pubmed/17460065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4314-06.2007
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