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CNS-Derived Interleukin-4 Is Essential for the Regulation of Autoimmune Inflammation and Induces a State of Alternative Activation in Microglial Cells

Regulation of inflammation in the CNS is essential to prevent irreversible cellular damage that can occur in neurodegenerative diseases such as multiple sclerosis (MS). We investigated the role of interleukin-4 (IL-4) in regulating CNS inflammation using the animal model of MS, experimental autoimmu...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ponomarev, Eugene D., Maresz, Katarzyna, Tan, Yanping, Dittel, Bonnie N.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672829/
https://ncbi.nlm.nih.gov/pubmed/17913905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1922-07.2007
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