Ca(2+)-Permeable AMPA Receptors Regulate Growth of Human Glioblastoma via Akt Activation

Evidence has been accumulated that glioblastoma cells release and exploit glutamate for proliferation and migration by autocrine or paracrine loops through Ca(2+)-permeable AMPA-type glutamate receptors. Here, we show that Ca(2+) signaling mediated by AMPA receptor regulates the growth and motility...

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Vydáno v:J Neurosci
Hlavní autoři: Ishiuchi, Shogo, Yoshida, Yukari, Sugawara, Kenichi, Aihara, Masanori, Ohtani, Toshiyuki, Watanabe, Takashi, Saito, Nobuhito, Tsuzuki, Keisuke, Okado, Haruo, Miwa, Akiko, Nakazato, Yoichi, Ozawa, Seiji
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672718/
https://ncbi.nlm.nih.gov/pubmed/17652589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2180-07.2007
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