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Hedgehog Signaling in the Subventricular Zone Is Required for Both the Maintenance of Stem Cells and the Migration of Newborn Neurons

We examined the postnatal consequences of removing Hedgehog signaling within the adult stem cell niche. Although at birth the subventricular zone appears normal in mice lacking Hedgehog signaling, by postnatal day 8 it is greatly impaired, and cell death is increased. In addition, both the quiescent...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Balordi, Francesca, Fishell, Gord
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672245/
https://ncbi.nlm.nih.gov/pubmed/17537964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1040-07.2007
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