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The Tau N279K Exon 10 Splicing Mutation Recapitulates Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 Tauopathy in a Mouse Model

Intracellular tau deposits are characteristic of several neurodegenerative disorders called tauopathies. The tau protein regulates the stability and assembly of microtubules by binding to microtubules through three or four microtubule-binding repeats (3R and 4R). The number of microtubule-binding re...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Dawson, Hana N., Cantillana, Viviana, Chen, Liling, Vitek, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672194/
https://ncbi.nlm.nih.gov/pubmed/17715352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5492-06.2007
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