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Rapid Tumor Necrosis Factor α-Induced Exocytosis of Glutamate Receptor 2-Lacking AMPA Receptors to Extrasynaptic Plasma Membrane Potentiates Excitotoxicity

The postinjury inflammatory response in the CNS leads to neuronal excitotoxicity. Our previous studies show that a major component of this response, the inflammatory cytokine tumor necrosis factor α (TNFα), causes a rapid increase in AMPA glutamate receptors (AMPARs) on the plasma membrane of cultur...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Leonoudakis, Dmitri, Zhao, Pingwei, Beattie, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671833/
https://ncbi.nlm.nih.gov/pubmed/18305246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5159-07.2008
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