Developing Postmitotic Mammalian Neurons In Vivo Lacking Apaf-1 Undergo Programmed Cell Death by a Caspase-Independent, Nonapoptotic Pathway Involving Autophagy

Previous studies have shown that caspases and Apaf-1 are required for the normal programmed cell death (PCD) in vivo of immature postmitotic neurons and mitotically active neuronal precursor cells. In contrast, caspase activity is not necessary for the normal PCD of more mature postmitotic neurons t...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Oppenheim, Ronald W., Blomgren, Klas, Ethell, Douglas W., Koike, Masato, Komatsu, Masaaki, Prevette, David, Roth, Kevin A., Uchiyama, Yasuo, Vinsant, Sharon, Zhu, Changlian
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671586/
https://ncbi.nlm.nih.gov/pubmed/18256270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4575-07.2008
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