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White Matter Vulnerability to Ischemic Injury Increases with Age Because of Enhanced Excitotoxicity
Stroke incidence increases with age and this has been attributed to vascular factors. We show here that CNS white matter (WM) is intrinsically more vulnerable to ischemic injury in older animals and that the mechanisms of WM injury change as a function of age. The mouse optic nerve was used to study...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6671573/ https://ncbi.nlm.nih.gov/pubmed/18256269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5137-07.2008 |
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